In the plant Cannabis sativa is possible to find more than 70 compounds called cannabinoids; some of them are in greater proportion than others and therefore are those who have received the most attention for its study, which has been determined with verifiable evidence medicinal / therapeutic / pharmacological properties.
The tetrahydrocannabinol or Δ9-THC is among the chemical components of cannabis, particularly among cannabinoids; the best studied and is responsible for many, if not most, of physical and psychoactive effects of cannabis. It is the main cannabinoid involved in producing “high”, “high”, “fly”. It is also the most abundant in most cannabis varieties which are on the market, but also has many proven medicinal effects.
It is a very good appetite stimulant and reduces nausea and vomiting, for these two reasons it is widely used in cancer patients undergoing chemotherapy. It also has analgesic properties moderate than in synergy with the CBD enhance the effect against pain, it is also anti-inflammatory. Other effects include relaxation, impaired senses visual, auditory, and olfactory. Also THC, other cannabinoid containing a phenol group possess antioxidant activity sufficient to protect neurons against oxidative stress thus is slight neuroprotective even been shown to stimulate neurogenesis, ie the creation of new neurons. In tests it has also proved useful in alleviating spasms and tremors. Furthermore it is proven that has a strong effect bronchodilator.
THC is an agonist (ie, a promoter) of the CB1 cannabinoid receptors, present mainly in the brain so that its greatest effects are on the functions carried this body. Its effect is markedly brain / mind increasing sensory functions such as vision, hearing, color sensitivity, also increases sexual arousal in men and women, also modifies the space / time perception. It produces a powerful feeling of euphoria, mental well-being and sharpens the mind encouraging curiosity and creativity.
In general, it is convinced that acute cannabis intoxication or chronic use causes changes in short-term episodic memory and working memory. Besides THC levels too high can cause the following side effects: spatial and temporal disorientation, tachycardia, nervousness, anxiety, and paranoia. For this reason, people with predisposition to schizophrenia, bipolar or the anxiety should avoid consuming cannabis varieties with high levels of THC. These side effects are generally limited by the presence of other cannabinoids CBD or CBN.
The Cannabidiol is another major cannabinoids present in the plant Cannabis sativa, it has gained importance in recent years because it produces no psychoactive effect and has many medicinal benefits.
The CBD is less so than the THC in most of the varieties available in the market, this because most growers always sought to obtain higher content of psychoactive cannabinoid (THC) aside varieties exhibited increased concentration of CBD. But with the discoveries about its medicinal effect, during the last years many growers and seed banks began to rescue from oblivion these varieties of cannabis, so it is now possible to find strains containing a ratio of THC / CBD 1: 1, that is, they have the same concentration of THC and CBD.
The most interesting property CBD is that behaves as an antagonist of THC, reducing the psychoactive effect of this, as not acting on cannabinoid receptors in the brain (CB1). So varieties with equal percentage of both cannabinoid not produce potent psychoactive effects, but important medicinal effects.
Among the medicinal effects of CBD the most important thing to note is the ability to induce death in cancer cells without affecting healthy cells of our body, as if it does chemotherapy. Currently many researchers are studying the CBD as an anticancer and have been found to be very effective in breast, colon and some type of brain cancer. It is also very proven to reduce seizures in people affected by epilepsy. It also helps to control psychotic disorders, depression and anxiety, and provide neuroprotective effects, especially those who recently suffered a stroke. Similarly as THC, it has anti-inflammatory, analgesic and helps to control nausea and vomiting.
The cannabinol may be referred to as the third best known marijuana cannabinoid is psychoactive like THC, and contributes approximately 10% of the psychoactive properties of the plant. When the THC and CBN are present at high levels, the CBN appears to reduce the paranoia and anxiety often associated with cannabis use. It also makes the user feel less “bad condition” and provides a clearer “high”, compared to THC, but ingesting too much can lead to feeling dizzy.
As for its medicinal properties it has shown that the CBN suppresses immune cell function, and shows an antiemetic effect (reduced nausea and vomiting) and anticonvulsant, although the latter two properties are much weaker than those found in THC and CBD. However, they are studying various derivative CBN for their pharmacological properties, the most known of them nabilone. It has been shown to improve the symptoms of fibromyalgia, chronic pain, Parkinson’s disease and multiple sclerosis, among others. It is also effective against inflammatory bowel diseases, particularly against ulcerative colitis.
Achieve higher levels of CNB in plants as a grower is not difficult and should definitely be considered when planting. When the plant material is exposed to air or UV light for a long period of time, THC becomes CBN, ie it is a degradation product of THC. Wait a little longer when the plants then produce buds with a higher content of CBN, when the trichomes have become more of a color instead of white amber / clear common are harvested. It is also known that flowers or buds that are more exposed to air during drying / curing have higher levels of CBN.
The CBN has a number of benefits, like the CBD and THC. Obtaining buds with a higher content of CBN is definitely an issue to consider. Cannabis can help with many different types of problems and these compounds are those who make it possible. Knowing what they do and how they affect the person when ingested is very important. CBN is as important as the THC and CBD when it is cannabis.